The findings of a recent study headed by Weill Cornell Medicine and NewYork-Presbyterian researchers, suggests that changes in a single gene allow dangerous gut bacteria to trigger the inflammation that underlies Crohn's disease.
Karolinska Institutet researchers have demonstrated that B lymphocytes, on which the efficient operation of the immune system depends, can occasionally cause more harm than good since their numbers sharply increase following intestinal trauma, impeding the healing process.
Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn's disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. These findings could one day help doctors better select targeted treatments for patients with this immune disorder.
B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing. The results, which are presented in the journal Immunity, can be of significance to the treatment of inflammatory bowel disease.
Washington [US], October 15 (ANI): Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a new study.
Washington [US], October 15 (ANI): Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a new study.
Columbia [US], August 3 (ANI): Compared to pregnant women without IBD, pregnant women with inflammatory bowel disease and their unborn children suffer more risks and problems. These are the conclusions of a recent study which examined the outcomes of more than 8 million pregnancies.
Helsinki [Finland], May 2 (ANI): A recent study at the University of Helsinki revealed that the fungal microbiota in the gut is more abundant and diverse in children treated with antibiotics compared with the control group even six weeks following the start of the antibiotic course.
Tokyo [Japan], February 14 (ANI): Ulcerative colitis, the inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract, also affects the innermost lining of the colon and rectum. It can be a debilitating condition and can sometimes lead to life-threatening complications. Most importantly, at present, it is incurable. A recent study on this, by researchers from Tokyo Medical and Dental University (TMDU), gave a ray of hope.
Washington [US], February 5 (ANI): A recent discovery by Weill Cornell Medicine researchers has said that a growth factor protein produced by rare immune cells in the intestine can protect against the effects of Inflammatory bowel disease (IBD), an umbrella term used to describe disorders that involve chronic inflammation of one's digestive tract.