It is possible to determine how quickly the disease might advance by detecting immune cells in the cerebrospinal fluid after diagnosing ALS, according to researchers.
Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system's T cells to attack tumour cells. Their introduction a decade ago marked a major advance in cancer therapy, but only 10 per cent to 30 per cent of treated patients experience long-term improvement. New findings could now bolster the effectiveness of immune-checkpoint therapy.
London [England], September 26 (ANI): Immune cell types that could be targeted to develop specific immunotherapies in chemotherapy-resistant breast cancers have been identified by the investigators.
Washington [US], July 2 (ANI): During a recent study, researchers identified a new mechanism that teaches immune cells-in-training to spare the body's own tissues while attacking pathogens.
Washington [US], June 28 (ANI): Researchers identify new mechanism that teaches immune cells-in-training to spare the body's own tissues while attacking pathogens. As part of this early education, specialized thymus cells 'pose' as different tissues, teaching the immune system how to recognize both friend and foe. Immune cells that mistakenly react to the body's own proteins are eliminated or reassigned to other jobs. The findings shed light on the origins of autoimmune diseases and on the maturation of the adaptive immune system.
Oslo [Norway], January 2 (ANI): A recent study has found that pregnancy is a challenge for the mother's immune system from the outset as half of the genes in the foetus are foreign to her body.
Washington [US], October 12 (ANI): Immune checkpoint inhibitors, which unleash the immune response against tumor cells, have revolutionized cancer treatment; however, the medications aren't effective in a large number of patients, including those with colorectal cancer.