UCLA researchers and their colleagues have discovered a new physics principle governing how heat transfers through materials, and the finding contradicts the conventional wisdom that heat always moves faster as pressure increases.
The study revealed the essential structural understandings of the mysterious but significant tankyrase protein, which is a key player in the development of bowel cancer.
New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.
In the brains of people with Alzheimer's disease, the protein amyloid- clumps together. The eventual deposition of these aggregates as so-called plaques results in damage to the brain's blood vessels and tissue
The protein medin is deposited in the blood vessels of the brains of Alzheimer's patients along with the protein amyloid-b. Researchers from DZNE have discovered this so-called co-aggregation. They have now published their observation in the renowned journal Nature. "Medin has been known for over 20 years, but its influence on diseases was previously underestimated. We were able to show that pathological changes in the blood vessels of Alzheimer's patients are significantly enhanced by medin," says Dr. Jonas Neher from the Tubingen site of Deutsches Zentrum fur Neurodegenerative Erkrankungen (DZNE), who led the study. The Hertie Institute for Clinical Brain Research in Tubingen, the University of Tubingen and several international institutions and cooperation partners were also involved in this long-term project.
The human body is made up of more than a billion cells that join to form the tissues and organs of our bodies. However, cells are dynamic structures that, using different techniques, move through the body to fulfil various functions, such as close wounds or carry nutrients to other tissues.
Study revealed a unique mechanism that promotes cancer cell spread, as well as providing a foundation for future research that may eventually lead to the discovery of possible new targets to combat cancer metastasis.
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