The study found protein is crucial in helping malignancies avoid immune attacks. The "fragile X mental retardation protein" (FMRP) is a protein that controls a network of genes and cells in the tumor microenvironment that help the tumor "hidden" from immune cells.
A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumours from immune detection and destruction.