In the brains of people with Alzheimer's disease, the protein amyloid- clumps together. The eventual deposition of these aggregates as so-called plaques results in damage to the brain's blood vessels and tissue
The protein medin is deposited in the blood vessels of the brains of Alzheimer's patients along with the protein amyloid-b. Researchers from DZNE have discovered this so-called co-aggregation. They have now published their observation in the renowned journal Nature. "Medin has been known for over 20 years, but its influence on diseases was previously underestimated. We were able to show that pathological changes in the blood vessels of Alzheimer's patients are significantly enhanced by medin," says Dr. Jonas Neher from the Tubingen site of Deutsches Zentrum fur Neurodegenerative Erkrankungen (DZNE), who led the study. The Hertie Institute for Clinical Brain Research in Tubingen, the University of Tubingen and several international institutions and cooperation partners were also involved in this long-term project.
Tubingen [Germany], February 16 (ANI): The universe is vast and has a lot of mysteries hidden in it. Discoveries made by astronomers help us in understanding our universe a little better. Now, a team of German astronomers, led by Professor Klaus Werner of the University of Tubingen, have discovered a strange new type of star covered in the by-product of helium burning.
Washington [US], November 28 (ANI): Insulin lowers the dopamine level in a specific region of the brain (striatum) that regulates reward processes and cognitive functions, among other things. This interaction can be an important driver of the brain's regulation of glucose metabolism and eating behaviour.
Berlin [Germany], November 23 (ANI): Researchers from the German Center for Diabetes Research (DZD) in Tubingen have shown that in the human brain, the hormone insulin also acts on the most important neurotransmitter for the reward system, dopamine.
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