A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell Medicine researchers.
Researchers have identified that people who inherit a faulty copy of the BRCA1 gene may develop mutations and cancer due to error-prone DNA replication and repair. When these individuals' cells are under stress, replication of the normal BRCA1 gene stalls because of the highly repetitive DNA sequences in the gene that create physical barriers to machinery that copies DNA.
According to a new study by Weill Cornell Medicine investigators, a typical gut bacterium that can spread through the body and cause a serious infection resists natural immune defences and antibiotics by enhancing its protective outer layer, known as the cell envelope.
COVID-19 patients placed on ventilators can take a long time to regain consciousness. New research from Weill Cornell Medicine, NewYork-Presbyterian, MIT, and Massachusetts General Hospital is now illustrating that these delays may serve a purpose: protecting the brain from oxygen deprivation.
Washington [US], October 15 (ANI): Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a new study.
Washington [US], October 15 (ANI): Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a new study.
New York [US], September 21 (ANI): According to a new study led by Weill Cornell Medicine researchers, aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson's disease via a cellular waste-ejection process.
Washington [US], August 14 (ANI): Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies.
Washington [US], August 10 (ANI): Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies.
Washington [US], July 17 (ANI): Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study.